Welcome to PsorVal.net

Psoriasis News -- ScienceDaily

Largest psoriasis meta-analysis to date yields new genetic clues (Wed, 24 May 2017)
The identification of 16 additional genetic markers will help researchers get closer to understanding how -- and why -- psoriasis develops.
>> Read More

Potential target for treatment of skin inflammation in eczema and psoriasis (Mon, 22 May 2017)
Superficially, psoriasis and atopic dermatitis may appear similar but their commonalities are only skin deep. Atopic dermatitis, also known as eczema, is primarily driven by an allergic reaction, while psoriasis is considered an autoimmune disease. Nevertheless, researchers were able to pinpoint a common driver of skin inflammation in both diseases.
>> Read More

Cannabinoids may soothe certain skin diseases, say researchers (Tue, 18 Apr 2017)
Cannabinoids contain anti-inflammatory properties that could make them useful in the treatment of a wide-range of skin diseases, according to researchers.
>> Read More

Severe psoriasis predominantly affects men (Fri, 24 Mar 2017)
The fact that men are overrepresented in psoriasis registers and consume more psoriasis care have long led researchers to believe that the common skin disease disproportionately affects men. A unique study with 5,438 Swedish psoriasis patients now reveals that women have a statistically significant lower incidence of severe psoriasis compared to men.
>> Read More

Inflammatory disease trigger revealed (Wed, 22 Feb 2017)
Scientists have revealed a potent inflammatory molecule released by dying cells triggers inflammation during necroptosis, a recently described form of cell death linked to inflammatory disease. The discovery could lead to new and existing medicines that target the molecule being investigated as a way of treating inflammatory diseases, such as psoriasis and inflammatory bowel disease.
>> Read More

Depression puts psoriasis patients at significantly greater risk of psoriatic arthritis (Wed, 22 Feb 2017)
Psoriasis is a lifelong disease that is associated with significant cosmetic and physical disability and puts patients at increased risk for many major medical disorders. A multidisciplinary team of researchers has found that psoriasis patients who developed depression were at a 37 percent greater risk of subsequently developing psoriatic arthritis, compared with psoriasis patients who did not develop depression.
>> Read More

Cytotoxic immune cell in sick and healthy skin a key to understanding vitiligo (Mon, 20 Feb 2017)
With the aid of thousands of skin biopsies and over a hundred kilograms of skin, researchers have observed how two subgroups of immune cell behave in healthy skin. This functional dichotomy is preserved in the inflammatory diseases psoriasis and vitiligo. The study opens the way for more targeted local treatments for patchy inflammatory skin disorders.
>> Read More

Treatment has no sufficient effect in one of five psoriasis patients (Thu, 02 Feb 2017)
A substantial part of people, one in five, undergoing systemic treatment for psoriasis (i.e. pills taken orally, injections or infusions) still have considerable problems with their disease, according to a recent study.
>> Read More

Why thick skin develops on our palms and soles, and its links to cancer (Wed, 01 Feb 2017)
Foot callouses/keratoderma (thickened skin) can be linked to cancer of the esophagus (gullet), report researchers.
>> Read More

Immune system's 'workaround' may explain heart disease in psoriasis patients (Thu, 08 Dec 2016)
Two new studies describe how the inflammatory response to psoriasis can alter levels of several immune system molecules, ultimately increasing a person’s risk of thrombosis, which can include fatal blood clots
>> Read More

Is an agent used to treat psoriasis aimed at the wrong target? (Wed, 30 Nov 2016)
The antibody ustekinumab is in use for treatment of psoriasis since 2009. It inhibits the underlying inflammation by neutralizing certain messengers of the immune system. Researchers now shows that one of these messengers could actually be helpful in battling the illness.
>> Read More

New insights into skin cells could explain why our skin doesn't leak (Tue, 29 Nov 2016)
The discovery of the shape and binding capability of epidermal cells could explain how skin maintains a barrier even when it is shedding. New research into how epidermal cells form a barrier may explain the paradox of how we can shed them without compromising our skin's integrity. It could also help us to understand what happens when it forms incorrectly, which could lead to conditions like psoriasis and eczema.
>> Read More

Fungal skin infections commonly misdiagnosed (Thu, 17 Nov 2016)
Dermatophyte infections, the most common kind of fungal infection in the skin, hair, or nails, affect an estimated 25 percent of the world's population and have accounted for 51 million outpatient visits over the last 10 years in the U.S. Now researchers report that fungal skin infections may be commonly misdiagnosed.
>> Read More

Skin bacteria could protect against disease (Fri, 11 Nov 2016)
There are more and more examples of the ways in which we can benefit from our bacteria. According to new research, this is true for the skin as well. The work has shown that the most common bacteria on human skin secrete a protein which protects us from the reactive oxygen species thought to contribute to several skin diseases. The protein has an equally strong effect on dangerous oxygen species as known antioxidants such as vitamin C and vitamin E.
>> Read More

Researchers identify a key molecule in psoriasis development (Tue, 04 Oct 2016)
A potential therapeutic target for the treatment of psoriasis has been identified. Psoriasis is a chronic inflammatory disease of the skin that affects up to a 2% of the population and which has still no cure. The study shows that the TREX2 gene has a relevant role in the inflammatory response that develops during the illness.
>> Read More

Research finally reveals reason for perplexing red skin disease (Tue, 20 Sep 2016)
There aren't any effective treatments for the disease with the hard-to-pronounce-name, ichthyosis. The rare and perplexing genetic disease causes skin to be disfigured by redness and dark scales across one's entire body. Now, for the first time, new research has found the reason that the disease causes the red skin and has a promising biologic drug to begin testing soon in clinical trials.
>> Read More

Comparing coronary artery calcium scores in patients with psoriasis, diabetes (Wed, 24 Aug 2016)
Assessing coronary artery calcium (CAC) is a measure of the severity of atherosclerosis (clogged arteries) and a cornerstone for screening for risk of future cardiac events. The inflammatory skin condition psoriasis has been associated with increased risk of cardiovascular disease. Type 2 diabetes is a high-risk disease associated with increased cardiovascular risk.
>> Read More

Immune breakthrough: Unscratching poison ivy's rash (Tue, 23 Aug 2016)
We all know that a brush with poison ivy leaves us with an itchy painful rash. Now researchers have discovered the molecular cause of this irritation. The finding brings us a step closer to designing agents to block this mechanism and sheds light on other serious skin conditions, such as psoriasis.
>> Read More

Plaque psoriasis patients find many treatments, but few satisfied with their current plan (Tue, 16 Aug 2016)
A new national survey in the United States of nearly 600 individuals with psoriasis, reveals that although patients have numerous treatment options, they have difficulty finding treatment plans that work. In addition, respondents reported a heavy emotional toll, with many feeling isolated and stigmatized due to the condition.
>> Read More

Combining biologic and phototherapy treatments for moderate-to-severe psoriasis (Wed, 10 Aug 2016)
Although the efficacy and safety of biologic and phototherapeutic treatments in treating moderate-to-severe psoriasis are well known, not all patients respond well to monotherapy and may require a combination of both types of therapy. There have been few studies investigating the safety and efficacy of combination treatment; now, a review shows that combination treatment is safe and viable.
>> Read More