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MedWorm: Psoriasis

Valeant And AstraZeneca To Partner On Brodalumab (Tue, 01 Sep 2015)
US and EU regulatory submission planned in moderate-to-severe psoriasis in Q4 2015 LAVAL, Quebec, Sept. 1, 2015 -- (Healthcare Sales & Marketing Network) -- Valeant Pharmaceuticals International, Inc. (NYSE: VRX and TSX: VRX) today announced that its a... Biopharmaceuticals, Dermatology, Licensing, DistributionValeant Pharmaceuticals, AstraZeneca, Brodalumab, psoriasis (Source: HSMN NewsFeed) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
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Morning Break: Wrongful Birth, NOAC Safety, Psoriasis Drug Revived (Tue, 01 Sep 2015)
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff (Source: MedPage Today OB/GYN)
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Ustekinumab Found to Be Effective in Adolescents With PsoriasisUstekinumab Found to Be Effective in Adolescents With Psoriasis (Tue, 01 Sep 2015)
Adolescents with moderate to severe psoriasis may respond to the human monoclonal antibody ustekinumab as well as adults, with no unexpected side effects, a new study found. Reuters Health Information (Source: Medscape Dermatology Headlines)
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Valeant picks up AstraZeneca psoriasis drug after Amgen exit (Tue, 01 Sep 2015)
(Reuters) - Canada's Valeant Pharmaceuticals International Inc is buying rights to AstraZeneca Plc's late-stage experimental psoriasis drug brodalumab after it was dropped by Amgen Inc in May. (Source: Reuters: Health)
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Allergic contact dermatitis and nail damage mimicking psoriasis caused by nail hardeners (Mon, 31 Aug 2015)
(Source: Contact Dermatitis)
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Pictorial representation of illness and self measure (PRISM): an effective tool to assess the burden of psoriasis (Sun, 30 Aug 2015)
ConclusionPRISM is a highly reliable tool and new approach to assess perceived burden of patients with psoriasis. It is easy to use and we recommend the application as an additional outcome measure in clinical trial settings. (Source: Journal of the European Academy of Dermatology and Venereology) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
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Biological therapy induces expression changes in Notch pathway in psoriasis (Sat, 29 Aug 2015)
This study aimed to determine mRNA expression levels by real-time RT-PCR, and protein expression levels, analysed by Western blot and immunohistochemistry, of some components of the Notch pathway, such as NOTCH1, NOTCH2, JAGGED1, and HES1 after biological treatments in psoriatic patients. mRNA and protein levels of NOTCH1, NOTCH2, JAGGED1 and HES1 were upregulated in skin samples from untreated psoriatic patients compared with normal controls. Biological therapy showed to downregulate differently the protein expression levels of the molecules under study. Our study suggests that Notch pathway components might be a potential therapeutic target against psoriasis. (Source: Archives of Dermatological Research)
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The positive impact of the new National Institute for Health and Care Excellence lipid guidelines on cardiovascular disease risk management in patients with psoriasis (Sat, 29 Aug 2015)
(Source: British Journal of Dermatology)
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Seronegative reactive spondyloarthritis and the skin (Fri, 28 Aug 2015)
Spondyloarthritidies represent a group of conditions affecting the axial and peripheral muscoloskeletal apparatus and are often associated with psoriasis, infections, and inflammatory bowel diseases. Other diseases included in this category are psoriatic arthritis, ankylosing spondylitis, and enteropathic arthritis. Reactive arthritis is an elusive spondyloarthritis, commonly occurring 1 to 3 weeks after a digestive or a genitourinary tract infection, in which microorganisms do not infect the joint directly. (Source: Clinics in Dermatology)
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Subepidermal autoimmune blistering lesion in a case of psoriasis successfully treated with cyclosporin (Fri, 28 Aug 2015)
(Source: The Journal of Dermatology)
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