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MedWorm: Psoriasis

Complete primary treatment failure of adalimumab in a patient with photoaggravated psoriasis (Thu, 24 Jul 2014)
(Source: Photodermatology, Photoimmunology and Photomedicine) MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
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Cutaneous erosions: a herald for impending pancytopenia in methotrexate toxicity. (Wed, 23 Jul 2014)
We report 3 rare presentations of MTX-induced cutaneous erosions, 2 fatalities occurring with MTX-induced psoriatic plaque erosions, and the sixth reported case of MTX-induced erosions with no prior history of psoriasis. Each were elderly patients on proton pump inhibitors with a history of chronic non-steroidal anti-inflammatory drug (NSAID) use. They all presented with acute onset of erosions after a recent change in their MTX dose. Pancytopenia followed in each case. Physicians' awareness of the sequelae in MTX-induced cutaneous erosions is imperative so MTX can be discontinued and treatment instituted to prevent fatal bone marrow suppression. PMID: 25046458 [PubMed - in process] (Source: Dermatol Online J)
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Dermatology on instagram. (Wed, 23 Jul 2014)
This study investigated the presence of dermatology-related content on Instagram. The most popular professional dermatological organizations, dermatology journals, and dermatology related patient advocate groups on Facebook and Twitter, determined from a prior study, were searched for established profiles on Instagram. In addition, dermatology-related terms (i.e. dermatology, dermatologist, alopecia, eczema, melanoma, psoriasis, and skin cancer) and dermatology-related hashtags (i.e. #dermatology, #dermatologist, #melanoma, #acne, #psoriasis, and #alopecia) were searched. None of the top ten dermatological journals or professional dermatological organizations were found on Instagram. Although only one of the top ten patient advocate groups related to dermatology conditions, Melanoma Resear...
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The use of ustekinumab in a patient with severe psoriasis and positive HBV serology (Wed, 23 Jul 2014)
We report the case of a patient with severe psoriasis with positive serology for the Hepatitis B virus, who received ustekinumab (a human monoclonal antibody against interleukin 12 and 23). In this patient, the use of ustekinumab did not reactivate the Hepatitis B virus. Given the high prevalence of chronic viral infections in patients who are candidates for biologic therapy, as well as the potential for reactivate chronic viral illness, randomized controlled studies are needed to assess the risks and benefits of such therapy in these populations. (Source: Anais Brasileiros de Dermatologia)
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Drugs for Psoriasis, Arthritis May Lower Diabetes Risk (Tue, 22 Jul 2014)
Drugs for psoriasis, arthritis may lower diabetes risk (Source: AARP.org News)
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SOOTHIX PSORIASIS AND SEBORRHEIC DERMATITIS FORMULA (Salicylic Acid) Lotion [Electrolyzed Innovations, LLC] (Tue, 22 Jul 2014)
Updated Date: Jul 22, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST)) MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
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Chinese medicine combined with calcipotriol betamethasone and calcipotriol ointment for Psoriasis vulgaris (CMCBCOP): study protocol for a randomized controlled trial (Tue, 22 Jul 2014)
DiscussionTo address the effectual remission of the YXBCM01 granule for PV, this trial may provide a novel regimen for PV patients if the granule can decrease relapse rate without more adverse effects.Trial registration: Chinese Clinical Trial Registry (www.chictr.org): ChiCTR-TRC-13003233, registered 26 May 2013. (Source: Epidemiologic Perspectives and Innovations)
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When anti-TNF fails, anti-IL12-23 is an alternate option in psoriasis and psoriatic arthritis (Fri, 18 Jul 2014)
Pacientes com psoríase e artrite psoriásica respondem à terapia anti-TNF, mas nem todos os pacientes mantêm uma resposta efetiva e alguns não respondem. Nesse artigo, demonstramos o papel de uma nova via patogenética que, até certo ponto, independe de TNF nesses pacientes. Anti-IL-12-23 é um modo terapêutico novo e alternativo para pacientes com resposta recalcitrante à medicação com anti-TNF.Patients with psoriasis and psoriatic arthritis respond to anti-TNF therapy, but not all patients maintain effective response, and some do not respond. In this article, we demonstrate the role of a new pathogenetic pathway to some extent TNF-independent in these patients. Anti-IL12-23 is a new and alternate mode of therapy for patients with recalcitrant response to anti-TNF. (Source: Revis...
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National Psoriasis Foundation awards 13 psoriasis research fellowships (Fri, 18 Jul 2014)
(National Psoriasis Foundation) Twelve residents and medical students each received a one-year, $50,000 National Psoriasis Foundation fellowship to study psoriasis. The fellowships aim to increase the number of scientists studying and treating psoriatic disease by encouraging promising doctors to dedicate their careers to the study of psoriasis as physician researchers. (Source: EurekAlert! - Medicine and Health)
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Helicobacter pylori infection and skin disorders. (Fri, 18 Jul 2014)
Authors: Kutlubay Z, Zara T, Engin B, Serdaroğlu S, Tüzün Y, Yilmaz E, Eren B Abstract Helicobacter pylori is a Gram-negative bacterium that has been linked to peptic ulcer disease, gastric lymphoma, and gastric carcinoma. Apart from its well-demonstrated role in gastroduodenal diseases, some authors have suggested a potential role of Helicobacter pylori infection in several extra-intestinal pathologies including haematological, cardiovascular, neurological, metabolic, autoimmune, and dermatological diseases. Some studies suggest an association between Helicobacter pylori infection and skin diseases such as chronic idiopathic urticaria and rosacea. There have also been few case reports documenting association between Helicobacter pylori and psoriasis vulgaris, Behçet's disease,...
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