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MedWorm: Psoriasis

Obesity, psoriasis, and microbiota: an unexplored dangerous connection? (Tue, 03 Mar 2015)
(Source: Dermatologic Therapy) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
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Serendipity and its role in dermatology (Tue, 03 Mar 2015)
Arijit Coondoo, Sujata SenguptaIndian Journal of Dermatology 2015 60(2):130-135Serendipity is a pleasant surprise of finding a particularly useful information while not looking for it. Significant historic events occurring as a result of serendipity include the discovery of the law of buoyancy (Archimedes principle) by the Greek mathematician Archimedes, of the Americas by Christopher Columbus and of gravity by Sir Isaac Newton. The role of serendipity in science has been immensely beneficial to mankind. A host of important discoveries in medical science owe their origin to serendipity of which perhaps the most famous is the story of Sir Alexander Fleming and his discovery of Penicillin. In the field of dermatology, serendipity has been responsible for major developments in the therapy of ...
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Zinc-responsive acral hyperkeratotic dermatosis-A novel entity or a subset of some well-known dermatosis? (Tue, 03 Mar 2015)
Conclusions: We here report a series of patients, discernible because of their uniform clinical presentation of acral hypekeratotic plaques and in showing a noticeable response to zinc. Clinical, histopathological and laboratory investigations were done to rule out diseases of similar morphology including psoriasis, acral necrolytic erythema and lichen simplex chronicus. Authors understand that further studies with greater number cases and more detailed investigations are required to establish exact etio-pathogenesis and nomenclature of this distinct subset of patients. (Source: Indian Journal of Dermatology)
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Psoriatic erythroderma and hypothalamus-pituitary axis suppression due to misuse of systemic steroid: Two challenging cases (Tue, 03 Mar 2015)
Gautam K Singh, Manas ChatterjeeIndian Journal of Dermatology 2015 60(2):194-197Adding corticosteroid in homeopathic pills, self medication of steroid in the backdrop permanent cure in cases of psoriasis is not very uncommon in clinical practice in Indian subcontinent. First case a 52 year man, a known case of psoriasis vulgaris with psoriatic arthropathy of 15 years duration received multiple modalities of therapies without any satisfactory response. He was on self medication of tab prednisolone 10 mg daily with Cushingoid features. Second case a 22 year old boy, a known case of psoriasis from last 06 years was on Homeopathic treatment with Cushinoid features. Tapering of systemic steroid in first case and discontinuation of homeopathic drug in second case resulted in erythroderma and fea...
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An open label prospective randomized trial to compare the efficacy of coal tar-salicylic acid ointment versus calcipotriol/betamethasone dipropionate ointment in the treatment of limited chronic plaque psoriasis (Tue, 03 Mar 2015)
Alexander NastIndian Journal of Dermatology 2015 60(2):198-198 (Source: Indian Journal of Dermatology)
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Remission of psoriasis and psoriatic arthritis during bevacizumab therapy for renal cell cancer: Erratum (Tue, 03 Mar 2015)
Koushik LahiriIndian Journal of Dermatology 2015 60(2):209-209 (Source: Indian Journal of Dermatology) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
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G-231A and G+70C polymorphisms of endothelin receptor type-A gene could affect the psoriasis area and severity index score and endothelin 1 levels (Tue, 03 Mar 2015)
Conclusion: Although there were no associations between studied polymorphisms and psoriasis susceptibility, the PASI score and EDN1 levels seem to be affected by EDNRA G-231A and G + 70C polymorphisms. (Source: Indian Journal of Dermatology)
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Histology of psoriatic erythroderma in infants: Analytical study of eight cases (Tue, 03 Mar 2015)
Conclusion: Regular AC and PC dilatation were the consistent histological findings observed in infants with erythrodermic psoriasis. These were the early findings observed in younger infants. Co-existence of psoriasis with atopic dermatitis may indicate a common pathogenic mechanism or an immunogenetic spin-off. (Source: Indian Journal of Dermatology)
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Emopamil binding protein mutation in conradi-hünermann-happle syndrome representing plaque-type psoriasis (Tue, 03 Mar 2015)
Kemal Ozyurt, Asli Subasioglu, Perihan Ozturk, Rahime Inci, Fuat Ozkan, Elena Bueno, Javier Cañueto, Rogelio González SarmientoIndian Journal of Dermatology 2015 60(2):216-216Conradi-Hünermann-Happle syndrome (CDPX2, OMIM 302960) is an inherited X-linked dominant variant of chondrodysplasia punctata which primarily affects the skin, bones, and eyes. CDPX2 patients display skin defects, including ichthyotic lesions, follicular atrophoderma, cicatricial alopecia, and less frequently ichthyosiform erythroderma, cataracts, and skeletal abnormalities consisting of short stature, asymmetric shortening of the limbs, epiphyseal stippling, and craniofacial defects. CDPX2 results from mutations in emopamil binding protein (EBP) gene. The aim of our study is to identify EBP ...
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Patient-assisted teledermatology practice: What is it? When, where, and how it is applied? (Mon, 02 Mar 2015)
Garehatty Rudrappa KanthrajIndian Journal of Dermatology, Venereology, and Leprology 2015 81(2):136-143Recent teledermatology practice has been focused on different models made possible by robust advances in information technology leading to consistent interaction between the patient and health care professionals. Patient-assisted teledermatology practice also called patient-enabled teledermatology or home based teledermatology is one such novel model. There is a lack of scientific literature and substantive reviews on patient-assisted teledermatology practice. The present article reviews several studies and surveys on patient-assisted teledermatology practice and outlines its advantages and barriers to clinical utility and analyses the potentiality of this concept. Incorporating patient-a...
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