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MedWorm: Psoriasis

[Review] Helminth therapy or elimination: epidemiological, immunological, and clinical considerations (Tue, 21 Oct 2014)
Deworming is rightly advocated to prevent helminth-induced morbidity. Nevertheless, in affluent countries, the deliberate infection of patients with worms is being explored as a possible treatment for inflammatory diseases. Several clinical trials are currently registered, for example, to assess the safety or efficacy of Trichuris suis ova in allergies, inflammatory bowel diseases, multiple sclerosis, rheumatoid arthritis, psoriasis, and autism, and the Necator americanus larvae for allergic rhinitis, asthma, coeliac disease, and multiple sclerosis. (Source: The Lancet Infectious Diseases) MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
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Benefits of Psoriasis Drug Secukinumab Outweigh RisksBenefits of Psoriasis Drug Secukinumab Outweigh Risks (Tue, 21 Oct 2014)
The benefits of Novartis AG's anti-inflammation drug outweighed the risks in using it to treat a type of psoriasis, staff reviewers at the U.S. Food and Drug Administration said. Reuters Health Information (Source: Medscape Dermatology Headlines)
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New Biologic for Psoriasis Gets FDA Panel Nod of ApprovalNew Biologic for Psoriasis Gets FDA Panel Nod of Approval (Tue, 21 Oct 2014)
FDA advisory panel unanimously recommends secukinumab, a new biologic drug class, for the treatment of plaque psoriasis in adults. Medscape Medical News (Source: Medscape Medical News Headlines)
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FDA Panel Backs Novel Biologic for Psoriasis (Mon, 20 Oct 2014)
(MedPage Today) -- IL-17a inhibitor secukinumab wins plaudits from outside advisers. (Source: MedPage Today Public Health)
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FDA panel unanimously backs Novartis' psoriasis drug (Mon, 20 Oct 2014)
(Reuters) - An advisory panel to the U.S. Food and Drug Administration unanimously recommended the use of Novartis AG's anti-inflammation drug in patients with a type of psoriasis, paving the way for its approval. (Source: Reuters: Health)
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Biological Therapies for Psoriasis: Effects on ReproductionBiological Therapies for Psoriasis: Effects on Reproduction (Mon, 20 Oct 2014)
Are biological therapies for psoriasis safe to use in the pregnant patient? What impact might they have on paternal fertility and mutagenicity? The British Journal of Dermatology (Source: Medscape Today Headlines) MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
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Dyson launches humidifier to combat eczema and psoriasis (Mon, 20 Oct 2014)
Dyson has unveiled a new product in Japan - a humidifier that can help combat a wide range of health problems (Source: Telegraph Health)
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Severe exacerbation of psoriasis after intravenous immunoglobulin in patient with multiple sclerosis that started during biologic therapy (Mon, 20 Oct 2014)
(Source: Journal of the European Academy of Dermatology and Venereology)
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Comparing treatment goals for psoriasis with treatment decisions in daily practice: results from a prospective cohort of patients with psoriasis treated with biologics: BioCAPTURE (Mon, 20 Oct 2014)
ConclusionsPhysicians acted in accordance with treatment goals in the majority of patient visits. In the patient group not achieving these goals, physicians should have modified therapy according to treatment goals but continued the same therapeutic regimen in the majority of visits. Optimizing therapy and defining barriers in the latter group might increase treatment results in daily practice psoriasis care. (Source: British Journal of Dermatology)
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Alcohol consumption amplifies immune suppression induced by ultraviolet radiation (Sun, 19 Oct 2014)
Psoriasis is a chronic, autoimmune-mediated, multisystem, inflammatory disorder that effects approximately 2% of the population. While psoriasis is not considered lethal, comorbidities include metabolic syndrome, atherosclerotic cardiovascular disease, depression, poor self-esteem, and self-destructive habits such as obesity, smoking and excess alcohol consumption. Moderate to severe psoriasis correlates with an increased risk of death, with heavy alcohol use acting as a major contributor to this excessive mortality. (Source: Alcohol)
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